Kidney Treatment

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Kidney Treatment Biography
Researchers at the University are developing a bio-artificial kidney that uses living kidney cells to duplicate nearly all the functions of a healthy organ. While still in the experimental stage, the bio-artificial kidney could one day provide life-saving treatment for thousands of people with serious kidney disease.

“The kidney is the first human organ for which a mechanical substitute—the kidney dialysis machine—was designed,” says H. David Humes, the John G. Searle Professor of Internal Medicine. “We believe it also will be the first organ to have a fully functioning, implantable substitute created with the new science of tissue engineering.”

Humes and his research team recently completed animal testing of a key component of the bio-artificial kidney, called a Renal Tubule Assist Device. This device is designed for use outside the body to treat acute kidney failure.

Each year in the United States, about 190,000 people face this life-threatening condition, in which the kidneys suddenly shut down as a result of infection or injury.

Individuals with acute renal failure typically spend at least 10 days in intensive care attached to a hemo-filtration unit, which removes toxic waste products from their blood. But even with advanced medical care, more than 50 percent of these patients die before their kidneys can recover.

In a study published in the May 1999 issue of Nature—Biotechnology, Humes describes how the Renal Tubule Assist Device, connected to a standard hemofiltration unit, helped improve kidney function in laboratory animals with acute renal failure.

According to Humes, kidney cells lining hollow fibers in the device reabsorb vital electrolytes, water and glucose filtered out of blood during hemofiltration, in addition to producing other important molecules. Without these substances, the patient cannot fight off infections and maintain a normal fluid balance.

Pending FDA approval, human clinical trials for the Renal Tubule Assist Device in patients with acute kidney failure could begin as early as this fall. Within five years, Humes hopes to develop additional components of the bio-artificial kidney for patients with chronic renal failure—a gradual deterioration of kidney function that currently affects over 300,000 people in the United States, a number that is growing by about six percent each year.

People with chronic kidney failure undergo kidney dialysis treatment several times each week to remove toxic waste products from their blood. The procedure is expensive and has serious side effects.

“Our goal is to bring all the components for a bio-artificial kidney together in one implantable device that will carry out all the functions of a natural kidney,” Humes says. “We hope that one day it will be available as an universal-donor organ. This could eliminate the shortage of kidneys for transplant, end long waiting times for transplant organs and replace dialysis as a treatment for chronic renal failure.”

Research on the bio-artificial kidney is being conducted at the Ann Arbor Veteran‘s Administration (VA) Medical Center. Funding is provided by the National Institutes of Health, the VA Research Service and Nephros Therapeutics Inc., a private company established to develop U-M research on kidney tissue engineering into commercial products. Nephros holds exclusive licensing rights to develop the technology; and the U-M has applied for several patents. The U-M, Nephros and Humes hold a financial interest in this new technology.

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Treatment

Kidney Function

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Kidney Function Biography
Haemodialysis is of vital importance for people with poorly functioning kidneys. If the kidneys are unable to do their job properly, such as removing waste products from the blood, haemodialysis offers, at least temporarily, a solution. During dialysis the blood is purified via a membrane. This process is highly burdensome for the patient and a very expensive method of treatment. Moreover, the ‘cleaning’ is inadequate. Large, protein-bound waste products are poorly removed by haemodialysis or sometimes not at all. In the human body, these substances are normally eliminated by the nephrons. Today’s haemodialysis equipment lacks this component of the kidney function, causing an accumulation of certain waste products. This partly explains why haemodialysis patients develop severe health complaints and require frequent hospital visits. What can we do about it? The ideal solution is kidney transplantation. Unfortunately, this is an option from which not enough people can benefit yet. Every improvement of haemodialysis is therefore extremely welcome.

Better haemodialysis
Work is now underway on the so-called BioKid, a bioreactor of kidney cells to remove toxins that remain after haemodialysis. The bioreactor is a good supplement to present-day haemodialysis and can make the lives of many kidney patients much more tolerable. In effect, BioKid mimics the function and operation of our nephrons. We can achieve this with ‘live membranes’ from special polymers that are covered with a bioactive layer on which human kidney cells can grow. Aside from these smart membranes, we have generated special long-lived kidney cells. With an innovative culture system that is also being developed these kidney cells can be widely used in the hospital or in the clinic. BioKid is an outstanding aid in improving the quality of haemodialysis treatments and in reducing the risk of complications such as cardiovascular problems resulting from the accumulation of toxic waste products. However, it will still take several years before the research is completed and this technique can actually be applied in patients.

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Kidney Function 

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What Is Kidney Function

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What Is Kidney Function Biography
The kidney's job is to process nearly 48 gallons of blood every day. They filter, cleanse, rid the body of toxic wastes and reabsorb nutrients and water. What they cannot use they excrete in the 1 - 2 litres of urine produced every day. The Chinese call the kidneys ‘the master organ’. The kidneys also filter and re-absorb phosphate and calcium from foods, promote strong bones and help secrete a hormone called erythropoietin which acts on bone marrow stem cells stimulating red blood cell production, renin, kinins, and prostaglandins. They also play an important part in controlling blood pressure and manufacturing the active form of vitamin D – cholecalciferol (or calcitriol) or 1,25 dihydroxy.
 
Detoxification
Detoxification takes place in the liver and kidneys. To help alleviate MS symptoms, it is vital that your body detoxifies properly. The problem is that inadequate drainage of toxins through the liver and kidneys can cause a build up of toxicity which in turn can cause extensive free-radical damage, poorer cell function, and disrupted energy production by the mitochondria in the cells. This leads to build up of lactic acid and more toxicity and you may then start experiencing symptoms of fatigue, pain, sickness, poor memory, brain fog, tingling/numbness and balance problems. Also, the brain gets damaged by toxins and free radicals because not enough oxygen can get to the brain. Hormone problems also develop due to injury caused to the hypothalamus. This can also cause temperature and hormone levels to become disrupted. There may also be things like mood swings and PMS
 
The Importance of the Kidneys in Detoxification
As the kidneys work together with the liver it is important that no detoxification programme is done without first supporting the kidneys and the liver. When kidney and liver function is sluggish toxic waste cannot be fully flushed from the body so is circulated around the body in the bloodstream. An overload of toxins can cause irritation and the whole of the urinary tract becomes more prone to infection. Normal kidney function may be interfered with - resulting in water retention, kidney stones and mineral deficiencies. Symptoms of sluggish kidneys include fatigue; a need to urinate frequently, especially at night; a decrease in amount of urine or hesitancy in urination; swelling of the ankles, feet and legs; puffiness around the eyes; low mood and mood swings; agitation; tension; irritability; difficulty concentrating; slow sluggish movements, restless, heavy legs; decreased sexual interest and erectile dysfunction.
 
How to Improve Sluggish Kidney Function
 
First, restrict protein as protein increases metabolic waste, which is something the kidneys must remove from the body. A food intolerance test will help to identify problem foods. Second, avoid chemicals and food additives. Third, maintain calcium, iron and magnesium levels. Magnesium deficiency can have a direct effect on kidney function because of its link to high blood pressure. It is important to eat magnesium rich foods – and these are included in most detoxification diets. Good sources are green vegetables, nuts, seeds and wholegrains. Also, chew food well - this helps digestive enzymes to break food down. Water is very important but too much can be harmful. Eight glasses of pure water a day is fine. Vegetables and fruit are high in water so this can count towards the daily water intake. Restrict alcohol and too much salt and avoid heavy meals. Also avoid fried foods, processed fats, caffeine, sugar, chocolate, dairy products and processed carbohydrates. Finally be cautious with all types of drugs and chemicals, get plenty of sleep and avoid heavy meals.
 
Bio Resonance Scanning
In my clinic I use a unique programme called ‘Bio Resonance Scanning’, an energy therapy based on the principle that every material structure in the universe radiates a unique energy signature or frequency. As individuals we are in fact frequency receivers, transducers and transmitters. The bio resonance technology is able to conduct a ‘conversation’ with the body through frequency patterns and is able to identify, through the process of resonance, the body’s response. It can seek out hidden stressors or imbalances that are putting stress on the system. This programme can identify chemical imbalances, vitamin/mineral imbalances, yeast, candida, mercury toxicity and food imbalances. The bio resonance programme is then able to neutralise the frequency of any toxin present. The programme works beyond removing toxins; it actually “rewires” the body by enhancing healthy frequencies using bioresonance technology. Psychological and emotional imbalances can interfere with the hormonal and endocrine system. This programme can identify these interferences and send a ‘balancing/treatment’ programme to the body for the body to heal itself.
 
Case: Annabel McVeigh, 34, from Hertfordshire was diagnosed with relapsing remitting MS in 2002. She had her first of three bio resonance scans in 2007. At Annabel’s first bio resonance scan comfortable cable connectors or electrodes were placed on her neck and around her wrist. The scanner then took half an hour to converse with the body. A computer printout showed how well the various body organs were working. The scan found that Annabel’s endocrine system, kidneys, liver and lymphatics needed rebalancing. It also uncovered food intolerances. “It was explained to me that I need to make sure I am breaking down my foods and that my detoxification pathways are clear. My body was holding on to toxic waste which can cause symptoms affecting my blood sugar balance, thyroid and kidney/liver strength,” says Annabel. A re-balancing programme was then drawn up by the scanner and bio-resonance patterns were sent to Annabel via the connection cables. After the first session a tiny silver rebalancing “capsule” was given to Annabel which she was told to carry round with her at all times in a pocket and which allowed the rebalancing to take place at a distance – by transmission in “remote mode”. Annabel thinks bio resonance has really worked for her. In 2007 she had a relapse which affected the movement of one of her hands – an area where she had had previous MS problems. After a bio resonance treatment, her hand recovered within a day.
 
Case: Carol Nunn, 61, from Hertford, was diagnosed in 1996. Carol first had a bio resonance scan in 2006. The scan showed that her body was not getting rid of harmful toxins and that some of the foods she was eating i.e. proteins, were not being absorbed properly and taking too many supplements was slowing down detoxification.The scan also identified emotional imbalances. Carol is now on a total ‘rescue’ programme. This consists of structural realignment, diet, supplements (including pre-biotics and pro-biotics), and emotional balancing. When having the bio-resonance scan Carol experienced a “draining and lightness” within her body, and afterwards said that the pain in her eyes and legs had lessened considerably. Her sleeping pattern has improved, walking and energy levels much better than before the treatment, in fact she is now in better health than ten years ago!
 
Case: Claire Conroy-Oldham, 35, from Watford, was diagnosed with MS in 2002. Claire had bio resonance scanning in 2006. The scan revealed her body needed a ‘clean up’. Says Claire: ‘I was advised to take certain supplements, have Cranio Sacral Therapy and avoid the foods I was intolerant to because they were causing stress on my system. These were sugar, alcohol, bread, cakes, sweets, fruit juices and yeast foods like malt, smoked and pickled foods. I wasn’t breaking down protein, and was advised to take digestive enzymes. Now, my eyes are excellent.”

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

What Is Kidney Function

About Kidney Disease

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About Kidney Disease Biography

Calcium and phosphorus, which are minerals, help build strong bones. Healthy kidneys help regulate the level of phosphorus in your blood by removing extra phosphorus. If your kidneys aren't working properly, eventually you'll probably have high phosphorus levels in your blood (hyperphosphatemia). Too much phosphorus decreases the level of calcium in your blood, which can lead to bone disease.

Your phosphorus needs may vary, depending on your kidney function. For adults with kidney disease, generally 800 to 1,000 milligrams (mg) of phosphorus a day is the limit. Many healthy adults eat almost double this amount.

Nearly every food contains some phosphorus. As a general rule, foods high in protein are also high in phosphorus. If you have an earlier stage of kidney disease, you'll likely be advised to limit your intake of phosphorus and protein. A reduced-protein diet helps limit the amount of waste that builds up in your blood.

If you have late stage kidney disease and you're on dialysis, the picture changes a bit. Dialysis removes protein (in the form of waste) from your blood, so your protein needs increase — but you'll still need to choose lower phosphorus foods. A registered dietitian can help you choose protein-rich foods that are lower in phosphorus.

Below is a partial listing of foods lower in phosphorus to help you identify substitutes for higher phosphorus foods. Although a food or drink may be low in phosphorus, you still need to watch portion sizes and limit the number of servings you eat or drink each day.

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

About Kidney Disease 

Disease Kidney

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Disease Kidney Biography
It depends on the type of magnetic resonance imaging (MRI) scan you're scheduled to have — an MRI with contrast or an MRI without contrast. Contrast agents, including gadolinium, are used to enhance some MRI scans. Contrast agents are injected into a vein in your hand or arm. Not all MRIs require a contrast agent.

There are no special concerns for people with kidney problems having an MRI without contrast.

However, there are concerns if people with kidney problems are given a gadolinium-based contrast agent during their MRI — especially if they have severe kidney failure (renal insufficiency).

Gadolinium-containing contrast agents may increase the risk of a rare, but serious, disease called nephrogenic systemic fibrosis in people with severe kidney failure. Nephrogenic systemic fibrosis triggers thickening of the skin, organs and other tissues. There's no effective treatment for this serious, debilitating disease.

Before you have an MRI, ask your doctor if a gadolinium-based contrast agent will be used. If the answer is yes, tell your doctor about your history of kidney problems. If possible, your doctor may select a different imaging test. In cases where an MRI with gadolinium is necessary despite the potential risks, your doctor may use the lowest possible dose of the form of gadolinium that has been associated with the fewest complications as well as consider hemodialysis immediately after the MRI with gadolinium.

Disease Kidney

Disease Kidney

Disease Kidney

Disease Kidney

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Disease Kidney

Disease Kidney

Artificial Kidney

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Artificial Kidney Biography
An additional line of research on renal regeneration focuses on development of living membranes for an intradialytic biological kidney support device. End-stage renal disease patients have uremic complications that result in high cardiovascular morbidity and a poor quality of life, despite hemodialysis. Uremia is caused by the retention of a large group of molecules with different physical and chemical properties that are not sufficiently cleared by hemodialysis. Within REFORM, a cell device (BioKid) will be developed capable of effective clearance of these toxins ex vivo. The BioKid will comprise of multiple so-called living membranes, i.e. tight monolayers of human renal epithelial cells that are grown on newly designed semi-permeable bioactive polymer membranes. A unique supramolecular approach will be used to develop a 2D bioactive polymer membrane that regulates long-lived monolayer integrity and cell viability under uremic conditions. The expertise and knowledge gained on the supramolecular 2D bioactive polymer membrane will be translated into a 3D configuration that will be applied in a simple in vitro set-up as a cell-aided intradialytic uremic toxin removal device. This will serve as a proof of principle for a more sophisticated device that can be used in the future to treat uremic symptoms in end-stage renal disease patients on dialysis.